before proceeding you should have [[Nextcloud]] installed, and having a dedicated domain pointing to your server. This domain should be different from nextcloud domain.
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You should also consider isntalling and configuring [[LetsEncrypt]] to have a dedicated cert per domain.
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In case you are limited in the use of extra domain you might use a dedicated port to use nginx externally, but this add some limit in term of ssl certificate, and we suggest to reconsider the dedicated domain.